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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   DR5 Blocking Peptide    

DR5 Blocking Peptide

Product Information
Primary Accession Q9QZM4
Gene ID 21933
Calculated MW 42165 Da
Additional Information
Gene ID 21933
Application & Usage The peptide is used for blocking the antibody activity of active DR5. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, MK, CD262, Tnfrsf10b, Dr5, Killer
Target/Specificity DR5
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsDR5 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tnfrsf10b
Synonyms Dr5, Killer
Function Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B. Essential for ER stress-induced apoptosis (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in heart, lung and kidney.
Research Areas
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$ 95.00
Cat# PBV10026b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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