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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Granzyme B Blocking Peptide    

Granzyme B Blocking Peptide

Product Information
Primary Accession P10144
Other Accession NP_004122
Gene ID 3002
Calculated MW 27716 Da
Additional Information
Gene ID 3002
Application & Usage The peptide is used for blocking the antibody activity of Granzyme B. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Granzyme B,, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMB, CGL1, CSPB, CTLA1, GRB
Target/Specificity Granzyme B
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsGranzyme B Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CGL1, CSPB, CTLA1, GRB
Function This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Cellular Location Cytoplasmic granule. Note=Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells
Research Areas
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$ 95.00
Cat# PBV10029b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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