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BCA-1/BLC (CXCL13), human recombinant protein
B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O43927 |
|---|---|
| Calculated MW | 10.1 kDa |
| Gene ID | 10563 |
|---|---|
| Gene Symbol | CXCL13 |
| Other Names | B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand, Angie, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13 |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; ≥95% |
| Recombinant | Yes |
| Results | 1.0-10 ng/ml. |
| Target/Specificity | BCA-1/BLC (CXCL13) |
| Application Notes | Centrifuge the vial prior to opening. Reconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can then be diluted into other aqueous buffers or store at 4°C for 1 week or -20°C for future use. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized from 10 mM TFA |
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Provided below are standard protocols that you may find useful for product applications.
Background
Human BCA-1 (B Cell-Attracting chemokine 1), also known as BLC or CXCL13, is a recently identified new CXC chemokines. Human BCA-1 is a highly effective attractant for human blood B lymphocytes, but was inactive on freshly isolated or IL-2 stimulated T lymphocytes, monocytes and neutrophils. The human BCA-1 is a 10.1 kDa protein containing 85 amino acid residues.
References
Gunn M.D.,et al.Nature 391:799-803(1998).
Legler D.F.,et al.J. Exp. Med. 187:655-660(1998).
Napolitano M.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
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