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Hsp70 Blocking Peptide

     
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Product Information
Primary Accession P54652
Gene ID 3306
Calculated MW 70021 Da
Additional Information
Gene ID 3306
Application & Usage The peptide is used for blocking the antibody activity of Hsp70. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Heat shock-related 70 kDa protein 2, Heat shock 70 kDa protein 2, HSPA2
Target/Specificity Hsp70
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsHsp70 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSPA2
Function In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Plays a role in spermatogenesis. In association with SHCBP1L may participate in the maintenance of spindle integrity during meiosis in male germ cells.
Cellular Location Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:P17156}. Note=Colocalizes with SHCBP1L at spindle during the meiosis process {ECO:0000250|UniProtKB:P17156}
Research Areas
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$ 95.00
Cat# PBV10044b
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