|Calculated MW||22067 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of Bim/Bod. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C|
|Other Names||Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, Bcl2l11, Bim|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||Bim/Bod Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces apoptosis and anoikis. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent.|
|Cellular Location||Membrane; Peripheral membrane protein Mitochondrion. Note=Associated with intracytoplasmic membranes|
|Tissue Location||Expressed in a number of B- and T-lymphoid cell lines.|
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