Eotaxin/CCL11, murine recombinant protein
Murine Eotaxin
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P48298 |
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Calculated MW | 8.4 kDa |
Gene ID | 20292 |
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Gene Symbol | Ccl11, Scya11 |
Other Names | Eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11 |
Gene Source | Mouse |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Results | 100-1000 ng/ml |
Target/Specificity | Eotaxin |
Application Notes | Reconstitute in H₂O to a concentration of 0.1-1 µg/ µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum. |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and then lyophilized with no additives. The protein may appear as a haze or film that is difficult to see at the bottom of the vial. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Murine eotaxin shares many of the biological and physical characteristics of human eotaxin. The chemokine exhibits a high chemotactic selectivity for eosinophils and belongs to the C-C family of chemokines, along with chemokines such as RANTES, MCP-3, and MIP-1 α. Murine eotaxin is an 8.4 kDa protein containing 74 amino acid residues.
References
Rothenberg M.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:8960-8964(1995).
Gonzalo J.-A.,et al.Immunity 4:1-14(1996).
Teuscher C.,et al.J. Immunol. 163:2262-2266(1999).
Carninci P.,et al.Science 309:1559-1563(2005).
Garcia-Zepeda E.A.,et al.Genomics 41:471-476(1997).
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