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Caspase-9 Blocking Peptide

     
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Product Information
Primary Accession Q8C3Q9
Other Accession BAA86895
Gene ID 12371
Calculated MW 49979 Da
Additional Information
Gene ID 12371
Application & Usage The peptide is used for blocking the antibody activity of Caspase-9. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Caspase-9, CASP-9, 3.4.22.62, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, Caspase-9 subunit p35, Caspase-9 subunit p10, Casp9, Mch6
Target/Specificity Caspase-9 (for 3136-100)
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCaspase-9 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Casp9
Synonyms Mch6
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage- induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Research Areas
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Discontinued
Cat# PBV10058b-50
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