|Calculated MW||22.4 kDa|
|Other Names||Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF, Androgen-induced growth factor, Heparin-binding growth factor 8|
|Application Notes||Centrifuge the vial prior to opening. Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.1-1 mg/ml. This solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Repeated freeze/thaw cycles will result in some loss of activity.|
|Storage||-20°C; Lyophilized in 10 mM Tris, pH 8.0 + 75 mM NaCl. The protein may appear as a haze or film, which may not be seen at the bottom of the vial.|
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Provided below are standard protocols that you may find useful for product applications.
Fibroblast Growth Factor-8 (FGF-8) is also known as Androgen-induced Growth Factor (AIGF), a heparin binding growth factor, which stimulates the proliferation and activation of cells that express the FGF receptors. Recombinant human FGF-8 is a 22.4 kDa protein containing 193 amino acid residues.
Tanaka A.,et al.FEBS Lett. 363:226-230(1995).
Ghosh A.K.,et al.Cell Growth Differ. 7:1425-1434(1996).
Gemel J.,et al.Genomics 35:253-257(1996).
Payson R.A.,et al.Oncogene 13:47-53(1996).
Tanaka S.,et al.Dig. Dis. Sci. 46:1016-1021(2001).
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