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Epiregulin (EREG), human recombinant protein

Epiregulin, EREG

Product info
Primary Accession O14944
Calculated MW 6.0 kDa
Additional Info
Gene ID 2069
Gene Symbol EREG
Other Names Epiregulin, EREG
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥97%
Assay2&Purity2 HPLC; ≥97%
Recombinant Yes
Results <2.0 ng/ml
Target/Specificity Epiregulin
Application Notes Reconstitute in sterile H₂O to 0.1–1 mg /ml. The solution can then further diluted to other aqueous solutions.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized from 0.5 mg/ml solution containing 20 mM PBS, pH 7.4 and 130 mM NaCl.
Citations (0)

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Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and Vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant human EREG produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa.

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$ 3,250.00
$ 185.00
Cat# PBV10076r
(40 western blots)
Availability: 5-7days
Bulk Size
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