|Calculated MW||17.6 kDa|
|Other Names||Fms-related tyrosine kinase 3 ligand, Short name=Flt3 ligand, Short name=Flt3L, SL cytokine|
|Application Notes||Reconstitute in H₂O to a concentration of 0.1 – 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.|
|Storage||-20°C; Sterile filtered and lyophilized with no additives. The protein may appear as a haze of film, which is difficult to see at the bottom of the vial.|
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Provided below are standard protocols that you may find useful for product applications.
Human flt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells. Recombinant human flt3-ligand is a soluble 17.6 kDa polypeptide containing 155 amino acid residues, which comprises the extraCellular domain of the transmembrane flt3-ligand protein.
Hannum C.,et al.Nature 368:643-648(1994).
Lyman S.D.,et al.Blood 83:2795-2801(1994).
Lyman S.D.,et al.Oncogene 11:1165-1172(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
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