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flt-3-Ligand, murine recombinant protein

Fms-related tyrosine kinase 3 ligand

Product info
Primary Accession P49772
Calculated MW 16.4 kDa
Additional Info
Gene ID 14256
Gene Symbol Flt3-L
Other Names Fms-related tyrosine kinase 3 ligand, Short name=Flt3 ligand, Short name=Flt3L, SL cytokine
Gene Source Mouse
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Results 5-8 ng/ml
Target/Specificity Flt-3 Ligand
Application Notes Reconstitute in H₂O to a concentration of 0.1 – 1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives.
Citations (0)

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Flt3-Ligand belongs to a small group of growth factors that regulate proliferation of early hematopoietic cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant form is the transmembrane which is biologically active on the cell surface. The proteolytically cleaved transmembrane isoform generates a soluble form, which is also biologically active. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand alone cannot stimulate proliferation, but synergizes well with other CSFs and interleukins to induce growth and differentiation. Recombinant murine flt3-Ligand is a 16.4 kDa protein containing 144 amino acid residues.

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$ 180.00
$ 3,750.00
$ 595.00
Cat# PBV10079r
(40 western blots)
Availability: 5-7days
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