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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   MeCP2 Blocking Peptide   

MeCP2 Blocking Peptide

Product Information
Primary Accession P51608
Gene ID 4204
Calculated MW 52441 Da
Additional Information
Gene ID 4204
Application & Usage The peptide is used for blocking the antibody MeCP2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2, MECP2
Target/Specificity MeCP2
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMeCP2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MECP2
Function Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Cellular Location Nucleus. Note=Colocalized with methyl-CpG in the genome
Tissue Location Present in all adult somatic tissues tested.
Research Areas
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$ 95.00
Cat# PBV10081b
(40 western blots)
Availability: 5-7days
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