Ceruloplasmin, Human Plasma recombinant protein
Ferroxidase
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P00450 |
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Calculated MW | 132.0 kDa |
Gene ID | 1356 |
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Gene Symbol | CP |
Other Names | Ferroxidase |
Gene Source | Human |
Source | Human plasma |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | HPLC; |
Recombinant | No |
Target/Specificity | Ceruloplasmin |
Application Notes | Reconstitute in deionized H₂O. Aliquot and store at –20°C. Avoid freeze-thaw cycles. |
Format | Lyophilized protein |
Storage | -20°C; Lyophilized from 50 mM potassium phosphate, pH 6.8, 100 mM KCl and 20 mM €-amino caproic acid + 5 mM EDTA. |
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Provided below are standard protocols that you may find useful for product applications.
Background
An acute-phase reactant. Increased levels are associated with normal pregnancy, rheumatoid arthritis, and cirrhosis. Decreased levels are associated with hepatolenticular degeneration (Wilson's Disease). An elevated level of Cp is found in patients with progressive tumors. Additionally, as Cp is a pro-oxidant, an elevated level is a sign of cardiovascular disease.
References
Koschinsky M.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:5086-5090(1986).
Daimon M.,et al.Biochem. Biophys. Res. Commun. 208:1028-1035(1995).
Mercer J.F.B.,et al.FEBS Lett. 203:185-190(1986).
Bingle C.D.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:3257-3261(1986).
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