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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   MyD88 Blocking Peptide   

MyD88 Blocking Peptide

Product Information
Primary Accession Q6Y1S1
Gene ID 301059
Calculated MW 33856 Da
Additional Information
Gene ID 301059
Application & Usage The peptide is used for blocking the antibody activity of MyD88. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Myeloid differentiation primary response protein MyD88, Myd88
Target/Specificity MyD88
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMyD88 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Myd88
Function Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).
Cellular Location Cytoplasm.
Research Areas
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$ 95.00
Cat# PBV10098b
(40 western blots)
Availability: 5-7days
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