IL-1 beta, human recombinant protein
Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediato
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P01584 |
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Calculated MW | 17.0 kDa |
Gene ID | 3553 |
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Gene Symbol | IL1B |
Other Names | Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Results | <0.1 ng/ml |
Target/Specificity | IL-1 beta |
Application Notes | We recommend a quick spin followed by reconstitution in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or stored at –20°C for future use. |
Format | Lyophilized protein |
Storage | -20°C; Lyophilized with no additives. |
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Provided below are standard protocols that you may find useful for product applications.
Background
IL-1β is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses including the activation of B and T cells. Recombinant human IL-1β is a 17.0 kDa protein containing 153 amino acid residues.
References
Auron P.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 81:7907-7911(1984).
March C.J.,et al.Nature 315:641-647(1985).
Clark B.D.,et al.Nucleic Acids Res. 14:7897-7914(1986).
Clark B.D.,et al.Nucleic Acids Res. 15:868-868(1987).
Nishida T.,et al.Biochem. Biophys. Res. Commun. 143:345-352(1987).
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