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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   RIP3 Blocking Peptide   

RIP3 Blocking Peptide

Product Information
Primary Accession Q9QZL0
Other Accession NP_001157580
Gene ID 56532
Calculated MW 53322 Da
Additional Information
Gene ID 56532
Application & Usage The peptide is used for blocking the antibody activity of RIP3. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Receptor-interacting serine/threonine-protein kinase 3,, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, mRIP3, Ripk3, Rip3
Target/Specificity RIP3
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsRIP3 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ripk3
Synonyms Rip3
Function Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.
Cellular Location Cytoplasm, cytosol. Cell membrane. Mitochondrion
Tissue Location Expressed in embryo and in adult spleen, liver, testis, heart, brain and lung
Research Areas
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$ 95.00
Cat# PBV10124b
(40 western blots)
Availability: 5-7days
Bulk Size
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