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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Smac/DIABLO Blocking Peptide    

Smac/DIABLO Blocking Peptide

Product Information
Primary Accession Q9JIQ3
Gene ID 66593
Calculated MW 26820 Da
Additional Information
Gene ID 66593
Application & Usage The peptide is used for blocking the antibody activity of Anti-Smac/Diablo. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Diablo homolog, mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase, Smac, Diablo, Smac
Target/Specificity Smac/DIABLO
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsSmac/DIABLO Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Diablo
Synonyms Smac
Function Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases (By similarity).
Cellular Location Mitochondrion. Note=Released into the cytosol when cells undergo apoptosis
Tissue Location Highest expression found in heart, liver, kidney and testis.
Research Areas
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$ 95.00
Cat# PBV10125b
(40 western blots)
Availability: 5-7days
Bulk Size
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