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IL-6, murine recombinant protein

IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2, IL-6, Interleukin HP-1, B-cel

Product info
Primary Accession P08505
Calculated MW 21.7 kDa
Additional Info
Gene ID 16193
Gene Symbol IL6
Other Names IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2, IL-6, Interleukin HP-1, B-cell hybridoma growth factor, B-cell stimulatory factor 2, CTL differentiation factor, Interferon beta-2.
Gene Source Mouse
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Results <0.02 ng/ml
Target/Specificity IL-6
Application Notes Reconstitute in H₂O to a concentration of 0.1-1.0 µg/ µl. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Lyophilized with no additives.
Citations (0)

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IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues.


van Snick J.,et al.Eur. J. Immunol. 18:193-197(1988).
Tanabe O.,et al.J. Immunol. 141:3875-3881(1988).
Chiu C.P.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7099-7103(1988).
Grenett H.E.,et al.Nucleic Acids Res. 18:6455-6455(1990).
Carninci P.,et al.Science 309:1559-1563(2005).

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$ 180.00
$ 595.00
$ 4,250.00
Cat# PBV10127r
(40 western blots)
Availability: 5-7days
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