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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   FasL Blocking Peptide   

FasL Blocking Peptide

Product Information
Primary Accession P41047
Gene ID 14103
Calculated MW 31442 Da
Additional Information
Gene ID 14103
Application & Usage The peptide is used for blocking the antibody activity of FasL. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Tumor necrosis factor ligand superfamily member 6, CD95 ligand, CD95-L, Fas antigen ligand, Fas ligand, FasL, CD178, Tumor necrosis factor ligand superfamily member 6, membrane form, Tumor necrosis factor ligand superfamily member 6, soluble form, Receptor-binding FasL ectodomain, Soluble Fas ligand, sFasL, ADAM10-processed FasL form, APL, FasL intracellular domain, FasL ICD, SPPL2A-processed FasL form, SPA, Faslg, Apt1lg1, Cd95l, Fasl, gld, Tnfsf6
Target/Specificity FasL
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFasL Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Faslg
Synonyms Apt1lg1, Cd95l, Fasl, gld, Tnfsf6
Function Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects (By similarity).
Cellular Location Isoform FasL: Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle lumen Lysosome lumen. Note=Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination. Colocalizes with the SPPL2A protease at the cell membrane (By similarity). Tumor necrosis factor ligand superfamily member 6, soluble form: Secreted. Note=May be released into the extracellular fluid, probably by cleavage form the cell surface
Research Areas
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$ 95.00
Cat# PBV10138b
(40 western blots)
Availability: 5-7days
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