IL-13, rat recombinant protein
NC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P42203 |
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Calculated MW | 12.7 kDa |
Gene ID | 116553 |
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Gene Symbol | IL13 |
Other Names | NC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789. |
Gene Source | Rat |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | HPLC; ≥95% |
Recombinant | Yes |
Results | 2-6 ng/ml |
Target/Specificity | IL-13 |
Application Notes | Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1β, IL-6, IL-8, and TNF-α resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. Recombinant rat IL-13 is an 11.9 kDa protein containing 109 amino acid residues.
References
Lakkis F.G.,et al.Biochem. Biophys. Res. Commun. 197:612-618(1993).
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