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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Caspase-10 Blocking Peptide   

Caspase-10 Blocking Peptide

     
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Product Information
Primary Accession Q92851
Other Accession AAD28403
Gene ID 843
Calculated MW 58951 Da
Additional Information
Gene ID 843
Application & Usage The peptide is used for blocking the antibody activity of caspase-10. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C.
Other Names Caspase-10, CASP-10, 3.4.22.63, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE-like apoptotic protease 4, Caspase-10 subunit p23/17, Caspase-10 subunit p12, CASP10, MCH4
Target/Specificity Caspase-10
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% sodium azide.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsCaspase-10 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASP10
Synonyms MCH4
Function Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP8 and CASP9. Hydrolyzes the small- molecule substrates, Tyr- Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Tissue Location Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon
Research Areas
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Discontinued
Cat# PBV10172b-50
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