|Calculated MW||42763 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of CCR2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||C-C chemokine receptor type 2, C-C CKR-2, CC-CKR-2, CCR-2, CCR2, CD192, Ccr2, Cmkbr2|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||CCR2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the CCL2, CCL7 and CCL12 chemokines. Transduces a signal by increasing intracellular calcium ion levels (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in lung, spleen, kidney, thymus and macrophages|
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