CCR3 Blocking Peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O54814 |
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Other Accession | NP_446410 |
Gene ID | 117027 |
Calculated MW | 41643 Da |
Gene ID | 117027 |
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Application & Usage | The peptide is used for blocking the antibody activity of CCR3. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C. |
Other Names | C-C chemokine receptor type 3, C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, CD193, Ccr3, Cmkbr3 |
Target/Specificity | CCR3 |
Formulation | 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | CCR3 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Ccr3 |
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Synonyms | Cmkbr3 |
Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed in spleen but not in astrocytes or microglia. |
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