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MCP-1 (MCAF), human recombinant protein

MCP1, SCYA2

     
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product info
Primary Accession P10148
Calculated MW 8.6 kDa
Additional Info
Gene ID 20296
Gene Symbol MCP-1
Other Names HC11, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte chemotactic protein 1, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2
Gene Source Mouse
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Results 4 - 15 ng/ml.
Sequence QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
Target/Specificity MCP-1/CCL2
Application Notes Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized with no additives
Citations (0)

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Background

Monocyte Chemoattractant Protein 1 (MCP-1), also known as CCL2, is thought to be produced by injured or infected tissues. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells. Recombinant mouse MCP-1 is a non-glycosylated protein, containing 76 amino acids and having a molecular mass of 8.6 kDa.

References

Kawahara R.S.,et al.J. Biol. Chem. 264:679-682(1989).
Rollins B.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:3738-3742(1988).
Teuscher C.,et al.J. Immunol. 163:2262-2266(1999).
van Damme J.,et al.Eur. J. Biochem. 199:223-229(1991).
Ueno M.,et al.J. Lipid Res. 54:734-743(2013).

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$ 180.00
$ 495.00
$ 2,750.00
Cat# PBV10178r
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