|Calculated MW||8.6 kDa.|
|Other Names||CCL7, MARC|
|Sequence||MQPDGTNSST CCYVKKQKIP KRNLKSYRKI TSSRCPWEAV IFKTKKGMEV CAEAHQKWVE EAIAYLDMKT STPKP|
|Application Notes||When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.|
|Storage||-20°C; Sterile filtered and lyophilized with no additives|
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Provided below are standard protocols that you may find useful for product applications.
Monocyte Chemotactic Protein 3 (MCP-3), also called CCL7, is chemokine produced by macrophages and some tumor cell lines. MCP-3 signals through three different G protein-coupled receptors, CCR1, CCR2, and CCR3. CCL7 chemoattracts monocytes and can regulate macrophage function. Recombinant rat MCP-3 is a non-glycosylated protein, containing 75 amino acids, with a molecular weight of 8.6 kDa.
Wang X.,et al.Brain Res. Mol. Brain Res. 71:304-312(1999).
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