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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   Rab5 Blocking Peptide   

Rab5 Blocking Peptide

Product Information
Primary Accession P20339
Gene ID 5868
Calculated MW 23659 Da
Additional Information
Gene ID 5868
Application & Usage The peptide is used for blocking the antibody activity of active Rab5. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Ras-related protein Rab-5A, RAB5A, RAB5
Target/Specificity Rab5
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsRab5 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB5A
Synonyms RAB5
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome Cytoplasmic vesicle. Cell projection, ruffle. Membrane. Cytoplasm, cytosol. Note=Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms
Research Areas
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$ 95.00
Cat# PBV10202b
(40 western blots)
Availability: 5-7days
Bulk Size
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