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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   FIAF Blocking Peptide   

FIAF Blocking Peptide

Product Information
Primary Accession Q9Z1P8
Other Accession BAC25242
Gene ID 57875
Calculated MW 45538 Da
Additional Information
Gene ID 57875
Application & Usage The peptide is used for blocking the antibody activity of FIAF. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, Angptl4, Farp, Fiaf, Ng27
Target/Specificity FIAF
Formulation 50 µ (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFIAF Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Angptl4
Synonyms Farp, Fiaf, Ng27
Function Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Cellular Location Secreted. Secreted, extracellular space, extracellular matrix. Note=The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4
Tissue Location Predominantly expressed in adipose tissue and is strongly up-regulated by fasting in white adipose tissue and liver.
Research Areas
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$ 95.00
Cat# PBV10204b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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