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Granzyme A, human recombinant protein

CTL tryptase, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, Hanukkah factor (H fact

Product info
Primary Accession P12544
Calculated MW 26.9 kDa
Additional Info
Gene ID 3001
Gene Symbol GZMA
Other Names CTL tryptase, Cytotoxic T-lymphocyte proteinase 1, Fragmentin-1, Granzyme-1, Hanukkah factor, H factor, HF
Gene Source Human
Source Mammalian cell expression system
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC; ≥95%
Recombinant Yes
Sequence Recombinant Human Granzyme A is produced with mammalian cells expression system. Target protein is expressed with sequence (Glu27-Val262) of Human granzyme a (Uniprot #P12544) fused with a polyhistidine tag at the C-terminus.
Target/Specificity Granzyme A
Application Notes Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 µg/ml.). This can further be diluted to other aqueous buffers.
Format Lyophilized protein
Storage -20°C; Lyophilized from a 0.2 µm filtered solution of 20 mM MES and150 mM NaCl, pH 5.5.
Citations (0)

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Granzyme A is a member of the granzyme family. Granzyme A is the most abundant serine protease in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A has a specific function in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262).


Gershenfeld H.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1184-1188(1988).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Schmutz J.,et al.Nature 431:268-274(2004).
Ruike Y.,et al.J. Hum. Genet. 52:172-178(2007).
Goralski T.J.,et al.Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.

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$ 225.00
$ 665.00
$ 3,950.00
Cat# PBV10210r
(40 western blots)
Availability: 5-7days
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