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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NHERF1/ EBP50 Blocking Peptide   

NHERF1/ EBP50 Blocking Peptide

Product Information
Primary Accession Q9JJ19
Gene ID 59114
Calculated MW 38830 Da
Additional Information
Gene ID 59114
Application & Usage The peptide is used for blocking the antibody activity of NHERF1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Na(+)/H(+) exchange regulatory cofactor NHE-RF1, NHERF-1, Ezrin-radixin-moesin-binding phosphoprotein 50, EBP50, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1, Slc9a3r1, Nherf, Nherf1
Target/Specificity NHERF1/ EBP50
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsNHERF1/ EBP50 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Slc9a3r1
Synonyms Nherf, Nherf1
Function Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatozoa. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Involved in the regulation of phosphate reabsorption in the renal proximal tubules (By similarity).
Cellular Location Cytoplasm. Apical cell membrane. Cell projection, filopodium Cell projection, ruffle. Cell projection, microvillus. Endomembrane system; Peripheral membrane protein. Note=Colocalizes with actin in microvilli-rich apical regions of the syncytiotrophoblast. Present in lipid rafts of T-cells Translocates from the cytoplasm to the apical cell membrane in a PODXL-dependent manner. Colocalizes with CFTR at the midpiece of sperm tail (By similarity).
Research Areas
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$ 95.00
Cat# PBV10211b
(40 western blots)
Availability: 5-7days
Bulk Size
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