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RANTES, human recombinant protein

Small inducible cytokine A5, CCL5, T-cell-specific RANTES protein, SIS-delta, T cell- specific prote

     
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Product info
Primary Accession P13501
Calculated MW 10.1 kDa
Additional Info
Gene ID 6352
Gene Symbol TCP228
Other Names Small inducible cytokine A5, CCL5, T-cell-specific RANTES protein, SIS-delta, T cell- specific protein P228, TCP228, chemokine (C-C motif) ligand 5, SISd, SCYA5, RANTES, D17S136E, MGC17164.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Results 1-10 ng/ml
Target/Specificity RANTES
Application Notes Reconstitute in H₂O to a concentration of 0.1-1 µg/ µl. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°c for future use.
Format Lyophilized protein
Storage -20°C; Lyophilized with no additives
Citations (0)
citation

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Background

RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

References

Schall T.J.,et al.J. Immunol. 141:1018-1025(1988).
Nomiyama H.,et al.J. Interferon Cytokine Res. 19:227-234(1999).
Capoulade-Metay C.,et al.Immunogenetics 58:533-541(2006).
Jang J.S.,et al.Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Zeng Q.P.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# PBV10219r-1
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