RANTES, human recombinant protein
Small inducible cytokine A5, CCL5, T-cell-specific RANTES protein, SIS-delta, T cell- specific prote
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P13501 |
---|---|
Calculated MW | 10.1 kDa |
Gene ID | 6352 |
---|---|
Gene Symbol | TCP228 |
Other Names | Small inducible cytokine A5, CCL5, T-cell-specific RANTES protein, SIS-delta, T cell- specific protein P228, TCP228, chemokine (C-C motif) ligand 5, SISd, SCYA5, RANTES, D17S136E, MGC17164. |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Results | 1-10 ng/ml |
Target/Specificity | RANTES |
Application Notes | Reconstitute in H₂O to a concentration of 0.1-1 µg/ µl. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°c for future use. |
Format | Lyophilized protein |
Storage | -20°C; Lyophilized with no additives |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
References
Schall T.J.,et al.J. Immunol. 141:1018-1025(1988).
Nomiyama H.,et al.J. Interferon Cytokine Res. 19:227-234(1999).
Capoulade-Metay C.,et al.Immunogenetics 58:533-541(2006).
Jang J.S.,et al.Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases.
Zeng Q.P.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.