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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TLR9 Blocking Peptide   

TLR9 Blocking Peptide

Product Information
Primary Accession Q9EQU3
Other Accession NP_112455
Gene ID 81897
Calculated MW 116412 Da
Additional Information
Gene ID 81897
Application & Usage The peptide is used for blocking the antibody activity of TLR9. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Toll-like receptor 9, CD289, Tlr9
Target/Specificity TLR9
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsTLR9 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Tlr9
Function Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in defense against systemic mouse cytomegalovirus infection. Controls lymphocyte response to Helicobacter infection.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist
Tissue Location Expressed in the basolateral region of gastric epithelial cells with high levels detected in antrum and body mucosa (at protein level). Detected in spleen and stomach at higher levels in C57BL/6 mice than BALB/C
Research Areas
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$ 95.00
Cat# PBV10232b
(40 western blots)
Availability: 5-7days
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