TGF-alpha, human recombinant protein
Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF
|Calculated MW||5.5 kDa|
|Other Names||Transforming Growth Factor-α, Sacroma growth factor, TGF-type I, ETGF|
|Application Notes||Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For most in vitro applications, TGF-α exerts its biological activity in the concentration range of 0.5 to 25 ng/ml.|
|Storage||-20°C; Sterile filtered and lyophilized with no additives|
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Provided below are standard protocols that you may find useful for product applications.
Transforming Growth Factor-α (TGF-α) stimulates the proliferation of a wide range of epidermal and epithelial cells. TGF-α has been shown to play a role in the autocrine growth of certain transformed cells. Human TGF-α is a 5.5 kDa protein containing 50 amino acid residues.
Derynck R.,et al.Cell 38:287-297(1984).
Jakowlew S.B.,et al.Mol. Endocrinol. 2:1056-1063(1988).
Qian J.F.,et al.Gene 132:291-296(1993).
Qian J.F.,et al.Am. J. Hum. Genet. 53:168-175(1993).
Machida J.,et al.Genomics 61:237-242(1999).
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