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TGF-beta1, human recombinant protein
Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01137 |
|---|---|
| Calculated MW | 25.0 kDa |
| Gene ID | 7040 |
|---|---|
| Gene Symbol | TGFB1 |
| Other Names | Transforming Growth Factor-β1, Differentiation inhibiting factor, Cartilage-inducing factor |
| Gene Source | Human |
| Source | CHO cells |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Results | <0.05 ng/ml |
| Target/Specificity | TGF-beta 1 |
| Application Notes | Reconstitution in H₂O to a concentration of 50 ug/ml (e.g., 5 ug/100 µl) will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4°C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at –20°C. |
| Format | Lyophilized protein |
| Storage | -20°C; Lyophilized from Sodium Citrate, pH3.5 buffer |
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Provided below are standard protocols that you may find useful for product applications.
Background
TGF-β1 (Transforming Growth Factor-β1) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
References
Derynck R.,et al.Nucleic Acids Res. 15:3188-3189(1987).
Derynck R.,et al.Nature 316:701-705(1985).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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