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Oct-2 Blocking Peptide

     
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Product Information
Primary Accession P09086
Other Accession AAA59978
Gene ID 5452
Calculated MW 51209 Da
Additional Information
Gene ID 5452
Application & Usage The peptide is used for blocking the antibody activity of Oct-2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Oct-2, Octamer-binding transcription factor 2, OTF-2, POU2F2, OCT2, OTF2
Target/Specificity Oct-2
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsOct-2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU2F2 (HGNC:9213)
Synonyms OCT2, OTF2
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654). Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874).
Cellular Location Cytoplasm. Nucleus.
Tissue Location Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
Research Areas
Citations (0)
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Discontinued
Cat# PBV10241b-50
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