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TPO, human recombinant protein

TPO, human recombinant

Product info
Primary Accession P07202
Calculated MW 102963 Da
Additional Info
Gene ID 7173
Gene Symbol TPO
Other Names Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Results <1 ng/ml
Target/Specificity TPO
Application Notes Reconstitution in purified H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA).
Format Lyophilized protein
Storage -20°C; Lyophilized with no additives
Citations (0)

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TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide, which contains the erythropoietin-like domain of the full length TPO protein.


Kimura S.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5555-5559(1987).
Libert F.,et al.Nucleic Acids Res. 15:6735-6735(1987).
Kimura S.,et al.Biochemistry 28:4481-4489(1989).
Barnett P.S.,et al.Nucleic Acids Res. 18:670-670(1990).
Rapoport B.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.

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$ 180.00
$ 3,900.00
$ 495.00
Cat# PBV10241r
(40 western blots)
Availability: 5-7days
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