TPO, murine recombinant protein
Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl li
|Calculated MW||18.7 kDa|
|Other Names||Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.|
|Results||< 1.0 ng/ml|
|Application Notes||Reconstitute in H₂O to a concentration of 0.5-1.0 mg/ml. Further dilutions of this solution should be made into buffer containing carrier protein or medium containing serum. This solution can be stored at 4°C for 1 week or –20°C for future use.|
|Storage||-20°C; Sterile filtered and lyophilized from 10 mM Tris, pH 8.0|
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Provided below are standard protocols that you may find useful for product applications.
TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulation levels of platelets in vivo. The murine TPO is a soluble 18.7 kDa protein containing 174 amino acid residues, which comprises the receptor binding domain of the Mpl-ligand protein.
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