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TWEAK, human recombinant protein

APO3L, DR3LG, TWEAK, TNFSF12

     
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Product info
Primary Accession O43508
Calculated MW 17.0 kDa
Additional Info
Gene ID 8742
Gene Symbol TNFSF12 
Other Names APO3L, DR3LG, TWEAK, TNFSF12
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Results <10 ng/ml.
Target/Specificity TWEAK
Application Notes Reconstitute in 10 mM Sodium Phosphate (pH 7.5) to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 7.5 + 0.1 M L-Arg.
Citations (0)

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Background

Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. TWEAK, like many other members of the TNF family, is able to induce interleukin-8 synthesis in a number of cell lines. The recombinant human TWEAK is a 17.0 kDa protein, comprising the TNF-like extraCellular domain of TWEAK

References

Chicheportiche Y.,et al.J. Biol. Chem. 272:32401-32410(1997).
Marsters S.A.,et al.Curr. Biol. 8:525-528(1998).
Pradet-Balade B.,et al.EMBO J. 21:5711-5720(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Zody M.C.,et al.Nature 440:1045-1049(2006).

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$ 209.00
$ 3,350.00
Cat# PBV10247r
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