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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   VDAC/Porin Blocking Peptide   

VDAC/Porin Blocking Peptide

Product Information
Primary Accession P21796
Gene ID 7416
Calculated MW 30773 Da
Additional Information
Gene ID 7416
Application & Usage The peptide is used for blocking the antibody activity of VDAC/Porin. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Voltage-dependent anion-selective channel protein 1, VDAC-1, hVDAC1, Outer mitochondrial membrane protein porin 1, Plasmalemmal porin, Porin 31HL, Porin 31HM, VDAC1, VDAC
Target/Specificity VDAC/Porin
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsVDAC/Porin Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name VDAC1
Synonyms VDAC
Function Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Cellular Location Mitochondrion outer membrane. Cell membrane
Tissue Location Heart, liver and skeletal muscle.
Research Areas
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$ 95.00
Cat# PBV10252b
(40 western blots)
Availability: 5-7days
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