|Calculated MW||30670 Da|
|Application & Usage||The peptide is used for blocking the antibody activity of Uroplakin III. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.|
|Other Names||Uroplakin-3a, UP3a, Uroplakin III, UPIII, UPK3A, UPK3|
|Formulation||50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.|
|Reconstitution & Storage||-20 °C|
|Precautions||Uroplakin III Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type I membrane protein Note=Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).|
|Tissue Location||Expressed in ureter.|
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