BAFF Receptor, human recombinant protein
human BAFF Receptor, h-BAFF Receptor, rh-BAFF Receptor, recombinant human BAFF Receptor, recombinant
|Calculated MW||7.7 kDa|
|Other Names||Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, Short name=BAFF-R, BLyS receptor 3, CD_antigen=CD268|
|Application Notes||Reconstitute in sterile H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.|
|Storage||-20°C; Sterile filtered and lyophilized from a solution (1 mg/ml) containing 20 mM phosphate buffer, pH 8.0, and 500 mM NaCl.|
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Provided below are standard protocols that you may find useful for product applications.
BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extraCellular portion of the full BAFFR protein.
Thompson J.S.,et al.Science 293:2108-2111(2001).
Dunham I.,et al.Nature 402:489-495(1999).
Yan M.,et al.Curr. Biol. 11:1547-1552(2001).
Kayagaki N.,et al.Immunity 17:515-524(2002).
Gordon N.C.,et al.Biochemistry 42:5977-5983(2003).
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