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BAFF Receptor, human recombinant protein

human BAFF Receptor, h-BAFF Receptor, rh-BAFF Receptor, recombinant human BAFF Receptor, recombinant

     
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Product info
Primary Accession Q96RJ3
Calculated MW 7.7 kDa
Additional Info
Gene ID 115650
Gene Symbol TR13C
Other Names Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF receptor, Short name=BAFF-R, BLyS receptor 3, CD_antigen=CD268
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥95%
Assay2&Purity2 HPLC; ≥95%
Recombinant Yes
Results 1-5 µg/ml
Target/Specificity BAFF Receptor
Application Notes Reconstitute in sterile H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Sterile filtered and lyophilized from a solution (1 mg/ml) containing 20 mM phosphate buffer, pH 8.0, and 500 mM NaCl.
Citations (0)
citation

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Background

BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extraCellular portion of the full BAFFR protein.

References

Thompson J.S.,et al.Science 293:2108-2111(2001).
Dunham I.,et al.Nature 402:489-495(1999).
Yan M.,et al.Curr. Biol. 11:1547-1552(2001).
Kayagaki N.,et al.Immunity 17:515-524(2002).
Gordon N.C.,et al.Biochemistry 42:5977-5983(2003).

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Discontinued
Cat# PBV10269r-10
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