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Pleiotrophin (PTN), human recombinant protein

PTN, Heparin Affin Regulatory Protein, HARP, Heparin-binding growth factor-8, HBGF-8, Osteoblast-Spe

Product info
Primary Accession P21246
Calculated MW 20.6 kDa
Additional Info
Gene ID 5764
Gene Symbol PTN
Other Names PTN, Heparin Affin Regulatory Protein, HARP, Heparin-binding growth factor-8, HBGF-8, Osteoblast-Specific Factor-1, OSF-1, Heparin-binding growth-associated molecule, HB-GAM, HBNF-1 Heparin-binding brain mitogen, Heparin-binding neurite outgrowth-promoting factor 1, HBBM, NEGF1.
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC; ≥98%
Recombinant Yes
Target/Specificity Pleiotrophin
Application Notes Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Lyophilized from 0.4X PBS, pH 7.2
Citations (0)

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Human Pleiotrophin (PTN) also called HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN (Pleiotrophin) and MK (midkine) are structural homologs, and are highly conserved among species. PTN plays an important role in development processes and promotion of neurite extension. Recombinant human PTN is a His-tag fusion protein (17.3 kDa) containing 136 amino acid residues of the PTN.


Tezuka K.I.,et al.Biochem. Biophys. Res. Commun. 173:246-251(1990).
Li Y.-S.,et al.Science 250:1690-1694(1990).
Kretschmer P.J.,et al.Growth Factors 5:99-114(1991).
Milner P.G.,et al.Biochemistry 31:12023-12028(1992).
Kretschmer P.J.,et al.Biochem. Biophys. Res. Commun. 192:420-429(1993).

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$ 4,250.00
$ 190.00
Cat# PBV10273r
(40 western blots)
Availability: 5-7days
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