PDGF-AA, human recombinant protein
Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1.
|Calculated MW||28.5 kDa|
|Other Names||Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1, Alpha platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a antigen, Platelet-derived growth factor alpha receptor|
|Results||< 1 ng/ml|
|Application Notes||Reconstitution in 10 mM acetic acid to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.|
|Storage||-20°C; Lyophilized with no additives|
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Provided below are standard protocols that you may find useful for product applications.
Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-AA is a 28.5 kDa A chain homodimer protein containing 250 amino acid residues.
Bonthron D.T.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1492-1496(1988).
Rorsman F.,et al.Mol. Cell. Biol. 8:571-577(1988).
Betsholtz C.,et al.Nature 320:695-699(1986).
Hoppe J.,et al.FEBS Lett. 223:243-246(1987).
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
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