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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   EMR2 Blocking Peptide   

EMR2 Blocking Peptide

Product Information
Primary Accession Q9UHX3
Other Accession A0JNV7
Gene ID 30817
Calculated MW 90472 Da
Additional Information
Gene ID 30817
Application & Usage The peptide is used for blocking the antibody activity of EMR2. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names EGF-like module-containing mucin-like hormone receptor-like 2, EGF-like module receptor 2, CD312, EMR2
Target/Specificity EMR2
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsEMR2 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EMR2
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell projection, ruffle membrane; Multi-pass membrane protein Note=Localized at the leading edge of migrating cells
Tissue Location Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested
Research Areas
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$ 95.00
Cat# PBV10292b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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