sRANK Ligand, murine recombinant protein
Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine,
|Calculated MW||19.4 kDa|
|Other Names||Soluble Receptor Activator of NFkB Ligand, TNFSF11, TRANCE, TNF-related activation-induced cytokine, OPGL, ODF, Osteoclast differentiation factor, Tumor necrosis factor ligand superfamily member 11, Receptor activator of nuclear factor kappa B ligand, RANKL, Osteoprotegerin ligand, CD254 antigen, sRANKL, sOdf.|
|Application Notes||Reconstitute in H₂O to a concentration of 0.1-1.0 mg /ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.|
|Storage||-20°C; Lyophilized from 5 mM Tris, pH 7.6 + 75 mM NaCl|
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Provided below are standard protocols that you may find useful for product applications.
Murine RANK (receptor activator of NF-kB) is a newly discovered member of the TNFR family, identified as a dendritic cell membrane protein. The recombinant murine sRANK Ligand is a soluble 19.4 kDa protein, comprising the 174 amino acid residue TNF homologous region of RANKL.
Wong B.R.,et al.J. Biol. Chem. 272:25190-25194(1997).
Anderson D.M.,et al.Nature 390:175-179(1997).
Lacey D.L.,et al.Cell 93:165-176(1998).
Yasuda H.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:3597-3602(1998).
Kodaira K.,et al.Gene 230:121-127(1999).
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