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FOXO3a Blocking Peptide

Product Information
Primary Accession O43524
Gene ID 2309
Calculated MW 71277 Da
Additional Information
Gene ID 2309
Application & Usage The peptide is used for blocking the antibody activity of FOXO2α. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30-60 minutes at 37°C.
Other Names Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3, FKHRL1, FOXO3A
Target/Specificity FOXO3a
Formulation 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsFOXO3a Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXO3
Synonyms FKHRL1, FOXO3A
Function Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=Translocates to the nucleus upon oxidative stress and in the absence of survival factors
Tissue Location Ubiquitous..
Research Areas
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$ 95.00
Cat# PBV10306b
(40 western blots)
Availability: 5-7days
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