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NCS-1 Blocking Peptide

Product Information
Primary Accession P62166
Other Accession AAP97256
Gene ID 23413
Calculated MW 21879 Da
Additional Information
Gene ID 23413
Application & Usage The peptide is used for blocking the antibody activity of active NCS-1. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, NCS1, FLUP, FREQ
Target/Specificity NCS-1
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsNCS-1 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NCS1
Synonyms FLUP, FREQ
Function Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N- type voltage-gated calcium channel (By similarity).
Cellular Location Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein Note=Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions
Research Areas
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$ 95.00
Cat# PBV10318b
(40 western blots)
Availability: 5-7days
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