|Calculated MW||32 kDa|
|Other Names||bone morphogenetic protein 10, BMP10, BMP 10|
|Application Notes||Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 µg BSA per 1 µg of protein). This solution can then be diluted into other aqueous buffers|
|Storage||-20°C; Sterile filtered and lyophilized with no additives|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-10 is essential for the proper development of the heart, but is not expressed until after cardiac patterning or looping are completed. Recombinant human BMP-10 is a 32 kDa disulfide-linked homodimer containing two 142 amino acid polypeptide chains.
Celeste A.J.,et al.Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mazerbourg S.,et al.J. Biol. Chem. 280:32122-32132(2005).
David L.,et al.Blood 109:1953-1961(2007).
Ye L.,et al.Cancer Sci. 101:2137-2144(2010).
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