BMP-13, human recombinant protein
bone morphogenetic protein 13, GDF-6, Cartilage-Derived Morphogenetic Protein-2, CDMP-2
|Calculated MW||27 kDa|
|Other Names||bone morphogenetic protein 13, GDF-6, Cartilage-Derived Morphogenetic Protein-2, CDMP-2|
|Application Notes||Reconstitute to 0.1-1.0 mg/ml in H₂O containing BSA (50 µg BSA per 1 µg of protein).|
|Storage||-20°C; Sterile filtered and lyophilized with no additives|
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Provided below are standard protocols that you may find useful for product applications.
BMPs (bone morphogenetic proteins) belong to the TGF-b superfamily of structurally related signaling proteins. These ligands mediate numerous physiological processes. BMPs initiate, promote and maintain cartilage and bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Expression of BMP-13 has been found in the hypertrophic chondrocytes of ossifying long bone centers. BioVision’s recombinant human BMP-13/CDMP-2 is a 27 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids polypeptide chains.
Guo J.H.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Tassabehji M.,et al.Hum. Mutat. 29:1017-1027(2008).
Asai-Coakwell M.,et al.Hum. Mol. Genet. 22:1432-1442(2013).
Asai-Coakwell M.,et al.Hum. Mol. Genet. 18:1110-1121(2009).
Ye M.,et al.Hum. Mol. Genet. 19:287-298(2010).
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