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VEGF-B, human recombinant protein

Vascular Endothelial Growth Factor-B, VEGFB

Product info
Primary Accession P49765
Calculated MW 19.63 kDa
Additional Info
Gene ID 7423
Gene Symbol VEGFB
Other Names Vascular Endothelial Growth Factor-B, VEGFB, VEGF-related factor
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Results 0.5-5.0 µg/ml.
Target/Specificity VEGF-B
Application Notes Reconstitute in 0.1% acetic acid to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C.
Format Lyophilized protein
Storage -20°C; Lyophilized without additives
Citations (0)

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VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, regulates angiogenesis and Vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surfaced-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a “cysteine knot” like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. Recombinant human VEGF-B is a 38.0 kDa disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains.


Grimmond S.,et al.Genome Res. 6:124-131(1996).
Olofsson B.,et al.J. Biol. Chem. 271:19310-19317(1996).
Olofsson B.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:2576-2581(1996).
Iyer S.,et al.J. Mol. Biol. 359:76-85(2006).

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$ 495.00
$ 3,450.00
$ 185.00
Cat# PBV10340r
(40 western blots)
Availability: 5-7days
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