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MMP-12 Blocking Peptide

Product Information
Primary Accession P39900
Other Accession NP_002417
Gene ID 4321
Calculated MW 54002 Da
Additional Information
Gene ID 4321
Application & Usage The peptide is used for blocking the antibody activity of active MMP-12. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37°C
Other Names Macrophage metalloelastase, MME,, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12, MMP12, HME
Target/Specificity MMP-12
Formulation 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% thimerosal.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsMMP-12 Blocking Peptide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP12
Synonyms HME
Function May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Found in alveolar macrophages but not in peripheral blood monocytes
Research Areas
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$ 95.00
Cat# PBV10343b
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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